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Best Picks for Cubs vs. Tigers

MLB: Detroit Tigers at Chicago Cubs
© Patrick Gorski-Imagn Images
  • What: MLB Regular Season Game
  • When: June 6, 2025
  • Who:   Chicago Cubs vs. Detroit Tigers
  • Time:  4:10 p.m. PST
  • Where: Comerica Park (Detroit, MI)

The Chicago Cubs (39-23) will take on the Detroit Tigers (41-23) this Friday in the opening game of a three-game series at Comerica Park, starting at 4:10 p.m. PST on Apple TV.

This is the first meeting of the season, though the Cubs won the series 2-1 last year.

The Cubs recently defeated the Washington Nationals 7-1 and have won four of their last five games, going 11-3 over their last 14 and 6-2 on the road.

Meanwhile, the Tigers lost to the Chicago White Sox 3-2 and have been inconsistent offensively, scoring two or fewer runs in four of their last six games. Despite this, they hold an 8-3 record over their previous 11.

In this game, RHP Ben Brown (3-3, 5.72 ERA) faces LHP Tarik Skubal (5-2, 2.26 ERA). Brown showed improvement in his last no-decision, throwing six scoreless innings against the Reds.

Skubal, solid at home, had a no-decision in his last start against the Royals.

At +165, the Cubs present good value against Skubal, especially given their strong performance against lefties. While Brown’s ERA isn’t reflective of his potential, this matchup seems like a good spot to back him.

Take the Cubs to pull off the upset over the Tigers in this one.

Best Bet: Cubs Money Line at +165 odds

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Tony Reyes is a sports betting analyst and reporter for Dice City Sports. You can follow him on X @TonyParlay.

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